97th DOG Annual Meeting 1999



U. Weber, C. Gittner

Random binary m-sequence stimuli are suitable to test retinal function in localized areas of the retina. For clinical use, the "1st order kernel" responses of mERGs were calibrated.

Material and methods: mERGs of 5 healthy volunteers were recorded 5 times at different days with a Roland Consult device (Wiesbaden, Brandenburg, Germany) using DTL electrodes and Cindatec software. Numerical values of the "1st order kernel" recordings were processed in EXCEL for statistical parameters (min, max, median, means and standard deviation) and compared with INSTAT (GraphPad). Right eyes were dialated, left eyes were not treated medically.

Results: Both in dilated and not dilated eyes a large scattering of the measurements, especially with smaller test areas, occurred. The least scattering was recorded in the overall area (3000 [deg2]): Amplitudes of the a- und b-waves: 5.227 + 1.764 [nV/deg2], 13.833 + 3.053 [nV/deg2]. A- und b-Wellenlatenzen: 17.567 + 1.613 [ms], 36.070 + 1.206 [ms]. Skalar 2.573 + 0.559 [uV/deg2], Fourier: 0.481 + 0.822 [uV/deg2].

Conclusions: As there ist a large scattering in 1st oder kernel mERG recordings, that ist still enlarging with smaller test units, the 1st order kernel mERG in the recording settings mentioned above should be used with multiple controls especially in the beginning of a clinical surveillance of a patient.

Augenklinik im St├Ądtischen Klinikum Braunschweig