97th DOG Annual Meeting 1999



H. Wenkel, N. X. Nguyen, U. Sch├Ânherr

Treatment of children with juvenile uveitis requires adequate control of inflammation though avoiding systemic or ocular side effects. The study was performed to evaluate the potential use of the laser flare cell meter in monitoring and adjustment of therapy in juvenile uveitis.

Patients and Methods: We monitored 20 children (10 girls and 10 boys) with an age range from 2.7 to 15.3 years presenting with juvenile iridocyclitis (10/20) or retinal vasculitis (10/20). During the follow-up period (median 25.2 years, range: 2 to 83 years) repeated clinical controls were performed. We recorded clinical data, present therapy, and measurements using the laser flare cell meter (Kowa FC-1000).

Results: The measured values with the laser flare cell meter were easily obtained and highly reliable even in this young patients. There was a good correlation between laser tyndallometry and clinical course. Relapses and a response to treatment could be seen at an early stage.

Conclusions: Laser tyndallometry offers a reliable, examiner-independent method to assess the intraocular inflammation in children with juvenile uveitis and to adjust the necessary treatment.

Department of Ophthalmology, University Erlangen-N├╝rnberg, Schwabachanlage 6, D-91054 Erlangen