97th DOG Annual Meeting 1999
FAMILIAL BILATERAL PARAFOVEAL RETINAL TELEANGIECTASIS IN TWO BROTHERS
B. Schröder, C. Prünte, J. Frei
Two cases of bilateral parafoveal retinal teleangiectasis in brothers are described.
Parafoveal retinal teleangiectasis is a developmental disorder of the retinal capillaries in which irregular capillary dilatation and leakage occur in the macular region. They occur mostly unilateral but also bilateral and are either idiopathic or secondary to diabetes mellitus, small branch-vein occlusion, radiation retinopathy, or carotid-artery obstruction. Visual decline occurs secondary to serous exudation, hard exudate deposition and macular edema.
Only occasional cases of parafoveal retinal teleangiectasis, especially of bi-lateral manifestation affecting two family members and raising suspicion of hereditary component have been documented.
In this case bilateral parafoveal retinal teleangiectasis in two brothers could be demonstrated by biomicroscopy and fluorescein angiography.
One patient showed a predominantly unilateral visual decline due to exuda-tion from the vessel anomalies, the other one was asymptomatic.
Complete ophthalmological examination revealed no other pathology, except the described one. IOP was normal.
One patient had vascular risk factors such as smoking, hypercholesterin-emia, arterial hypertension, had undergone a femoralis bypass operation and in october 1997 he had an episode of Malaria tertiana. The other patient was healthy.
Examinations of the relatives were normal, however, due to the age of the examined persons (younger than 28 years) no definitive statement could be made, because the disease usually manifests itself in the 4th decade of life.
Altogether these and the other few described cases show that there could be a hereditary component in this disease.
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