97th DOG Annual Meeting 1999
FLUORESCENCE ANGIOGRAPHIC AND CLINICAL FINDINGS IN PATIENTS WITH RETINAL VASCULITIS
H. Wenkel, D. Krist, U. Schönherr
To characterize the fluorescence angiographic findings in patients with retinal vasculitis.
Patients and Methods: In a retrospective fashion we re-evaluated all fluorescence angiographies performed between 1988 and 1998 in patients with the clinical diagnosis of retinal vasculitis
Results: Clinical data and fluorescence angiographies were available from 203 eyes of 173 patients with retinal vasculitis. There were 71 female and 127 male patients with an age range from 10 to 87 years (median: 34.5 years). Final diagnosis was immunological (21), infectious (20), sarkoidosis (10), BehVet's disease (14), Eales disease (7), unknown (95), or other (6). Angiographic findings distributed evenly among the different diagnostic groups were central (137/203) and peripheral (127/203) retinal vasculitis, retinal hemorrhagies (62/203), cystoid macular edema (63/203), capillary drop out (52/203), cotton-wool spots (31/203), and parapapillary retinal neovascularization (15/203). In patients with BehVet's disease there was a significant higher frequency of papilledema (p=0.0002), retinitis (p=0.01), and choroidal vasculitis (p=0.001). Eyes with Eales disease presented the highest number of peripheral retinal neovascularisation (p<0.0001). Choroiditis (p=0.001), papilledema (p=0.0064), arterial involvement (p=0.006), and retinitis (p=0.0001) were more frequently seen in eyes with infectious vasculitis.
Conclusions: Fluorescence angiography in retinal vasculitis is not only necessary to reveal retinal capillary drop out but can also provide important diagnostic clues to the underlying disease.
Department of Ophthalmology, University Erlangen-Nürnberg, Schwabachanlage 6, D-91054 Erlangen